Crypto Basics

Are There Crypto Indices for DeFi, AI, and Other Sectors? Exploring Thematic Index Investing in 2025

Want exposure to trending crypto themes like DeFi, AI, and Memecoins? Learn about the top sector-based crypto indices in 2025 and how to invest in the best narratives with less risk.
Token Metrics Team
8 min
MIN

In the fast-moving world of crypto, one of the smartest ways to invest in 2025 is by aligning your portfolio with emerging narratives. Whether it’s DeFi, AI, Memecoins, or Real World Assets (RWAs), crypto’s growth is fueled by themes—and the easiest way to capitalize on them is through sector-based crypto indices.

But are there crypto indices tailored to specific sectors?
Absolutely. In fact, thematic crypto indices are one of the hottest trends in index-based investing right now.

This article explores the most popular sector-based crypto indices in 2025, how they work, and how you can use them to build a diversified, trend-aligned portfolio.

What Is a Thematic or Sector-Based Crypto Index?

A sector-based crypto index is a basket of cryptocurrencies selected based on a specific theme or market narrative. Instead of tracking the overall market, these indices focus on high-growth areas such as:

  • Decentralized Finance (DeFi)
  • Artificial Intelligence (AI) Tokens
  • Memecoins
  • Real World Assets (RWA)
  • Layer 1 Blockchains
  • Gaming / Metaverse

Each index includes multiple tokens within that category, allowing investors to gain exposure to the entire theme without picking individual winners.

Why Sector Indices Matter in 2025

In today’s market, performance is narrative-driven. A single meme can send a coin flying, or a regulatory shift can pump RWAs. Sector indices help investors:

âś… Capitalize on trends early
âś… Avoid single-token risk
âś… Ride sector momentum without constant research
âś… Balance exposure across tokens within a theme

Instead of trying to guess which AI token will win, you can hold the AI Index and benefit from the entire trend.

Top Sector-Based Crypto Indices in 2025

Here are the most popular and best-performing thematic indices this year:

1. Token Metrics AI Tokens Index

Focus: Artificial Intelligence & Agent Economy
Constituents: FET, AGIX, GRT, TAO, NUM, OCEAN
Management: AI-powered with weekly rebalancing

Why It’s Hot:
AI is dominating tech and crypto alike. This index tracks high-conviction AI tokens and rotates into bullish ones each week. Its performance outpaced most passive indices during Q1 2025.

2. Token Metrics DeFi Index

Focus: Core DeFi protocols
Constituents: AAVE, LDO, UNI, RUNE, DYDX, GMX
Management: AI-managed, rebalanced weekly

Why It’s Hot:
DeFi is crypto’s infrastructure. This index rotates into projects showing strength in TVL, volume, and sentiment—giving you DeFi exposure without the need to manage protocol risk manually.

3. Token Metrics Memecoin Index

Focus: Viral meme tokens
Constituents: DOGE, SHIB, PEPE, WIF, BONK, FLOKI
Management: AI-powered signals and weekly adjustments

Why It’s Hot:
This index tracks social momentum and market sentiment, allowing traders to ride the waves while mitigating downside through AI-powered exits.

4. Token Metrics RWA Index

Focus: Real World Asset tokens
Constituents: MKR, ONDO, POLYX, XDC, CFG
Management: Thematic + risk-adjusted AI overlay

Why It’s Hot:
The RWA narrative is exploding as institutions tokenize bonds, treasuries, and assets. This index includes top-performing RWA projects with liquidity and regulatory traction.

5. Token Metrics Layer 1 Index

Focus: Smart contract platforms
Constituents: ETH, SOL, AVAX, NEAR, SUI, TON
Management: Passive or AI-optimized version

Why It’s Hot:
The infrastructure battle among Layer 1s continues. This index provides broad exposure to the platforms that power most of Web3.

6. Index Coop DPI (DeFi Pulse Index)

Focus: Leading Ethereum DeFi protocols
Constituents: AAVE, UNI, COMP, SNX, LRC
Management: DAO-governed, passive rebalance

Why It’s Hot:
DPI is the OG DeFi index—trusted, decentralized, and consistently rebalanced on-chain.

7. Phuture Custom Indices

Focus: User-created strategies
Constituents: Fully customizable
Management: On-chain rules, community-driven

Why It’s Hot:
Create your own sector index or invest in curated strategies. Fully composable within DeFi.

How to Choose the Right Sector Index

Choosing the best sector-based index depends on your goals and your belief in specific narratives.

AI vs. Passive Sector Indices

Many sector indices today are AI-powered, meaning they adjust weights and tokens dynamically based on real-time data. This is especially useful in volatile or hype-driven narratives (like Memecoins or AI tokens).

Where to Invest in Sector-Based Indices

Here’s where to find and invest in thematic indices:

  • âś… Token Metrics – Sector-specific AI indices with weekly signals
  • âś… Index Coop – Ethereum-based DeFi indices with DAO governance
  • âś… Phuture – On-chain, user-customized index strategies
  • âś… Set Protocol – Technical and trend-driven portfolios
  • âś… Centralized Brokers – Limited thematic access (e.g., Bitwise)

You can access these using fiat, stablecoins, or crypto wallets depending on the platform.

Final Thoughts: Sector Indices Help You Invest in What Matters

In 2025, the biggest opportunities in crypto are often found in narrative-driven sectors. Whether it’s AI, DeFi, Memecoins, or tokenized real-world assets, sector-based crypto indices offer:

  • Smart diversification
  • Aligned exposure to growing trends
  • Hands-free portfolio management
  • Reduced risk of picking the wrong token

For the best results, explore platforms like Token Metrics, where AI-enhanced sector indices help you adapt to the market and capitalize on breakout themes with data-backed precision.

Build Smarter Crypto Apps &
AI Agents in Minutes, Not Months
Real-time prices, trading signals, and on-chain insights all from one powerful API.
Grab a Free API Key
Token Metrics Team
Token Metrics Team

Recent Posts

Research

How API Calls Power Modern Apps

Token Metrics Team
5
MIN

APIs are the lingua franca of modern software: when one system needs data or services from another, it issues an API call. For developers and analysts working in crypto and AI, understanding the anatomy, constraints, and best practices around api calls is essential to building resilient integrations and reliable research pipelines.

What is an API call and why it matters

An API call is a request sent from a client to a server to perform an action or retrieve information. The request specifies an endpoint, method (GET, POST, etc.), headers (for authentication or metadata), and often a body (JSON or other payloads). The server processes the request and returns a response with a status code and data. In distributed systems, api calls enable modularity: microservices, exchange endpoints, data providers, and AI agents all communicate via these standardized exchanges.

For teams integrating market data, on-chain analytics, or AI models, api calls are the mechanism that moves structured data from providers to models and dashboards. Latency, reliability, and data integrity of those calls directly affect downstream analysis, model training, and user experience.

Protocols and common patterns for api calls

There are several common protocols and patterns you will encounter:

  • REST (HTTP/HTTPS): Resource-based endpoints with methods like GET, POST, PUT, DELETE and JSON payloads. It is simple and ubiquitous for public data APIs.
  • RPC (Remote Procedure Call): Calls invoke functions on a remote server (examples include JSON-RPC used by many blockchain nodes).
  • WebSocket / Streaming: Persistent connections for real-time updates, frequently used for trade feeds and live on-chain events.
  • Webhooks: Server-initiated HTTP callbacks that push events to your endpoint, useful for asynchronous notifications.

Choosing the right pattern depends on the use case: low-latency trading systems favor streaming, while periodic snapshots and historical queries are often served over REST.

Anatomy of an api call: headers, payloads, and responses

Understanding the pieces of a typical API request helps with debugging and design:

  1. Endpoint URL: The path identifying the resource or action (e.g., /v1/price or /rpc).
  2. HTTP method: GET for retrieval, POST for creation or complex queries, etc.
  3. Headers: Include authentication tokens (Bearer, API-Key), content-type, and rate-limit metadata.
  4. Body / Payload: JSON, form-encoded data, or binary blobs depending on the API.
  5. Response: Status code (200, 404, 429, 500), response body with data or error details, and headers with metadata.

Familiarity with these elements reduces time-to-diagnosis when an integration fails or returns unexpected values.

Security, authentication, and safe key management

APIs that provide privileged data or actions require robust authentication and careful key management. Common approaches include API keys, OAuth tokens, and HMAC signatures. Best practices include:

  • Use least-privilege API keys: limit scopes and rotate credentials regularly.
  • Avoid embedding keys in client-side code; store them in secure vaults or server-side environments.
  • Require HTTPS for all api calls to protect payloads in transit.
  • Log access events and monitor for anomalous usage patterns that indicate leaked keys.

These practices help prevent unauthorized access and reduce blast radius if credentials are compromised.

Rate limits, pagination, and observability for robust integrations

Service providers protect infrastructure with rate limits and pagination. Common patterns to handle these include exponential backoff for 429 responses, caching frequently requested data, and using pagination or cursor-based requests for large datasets. Observability is critical:

  • Track latency, error rates, and throughput per endpoint.
  • Implement alerting on rising error ratios or slow responses.
  • Use tracing and request IDs to correlate client logs with provider logs during investigations.

Monitoring trends in api call performance allows teams to proactively adjust retry strategies, request batching, or move to streaming alternatives when appropriate.

Testing, debugging, and staging strategies

Reliable integrations require systematic testing at multiple levels:

  • Unit tests: Mock API responses to validate client logic.
  • Integration tests: Run against staging endpoints or recorded fixtures to validate end-to-end behavior.
  • Load tests: Simulate traffic patterns to surface rate-limit issues and resource constraints.
  • Replay and sandboxing: For financial and on-chain data, use historical replays to validate processing pipelines without hitting production rate limits.

Tools like Postman, HTTP clients with built-in retries, and API schema validators (OpenAPI/Swagger) speed up development and reduce runtime surprises.

Build Smarter Crypto Apps & AI Agents with Token Metrics

Token Metrics provides real-time prices, trading signals, and on-chain insights all from one powerful API. Grab a Free API Key

What is an API call?

An api call is a client request to a server asking for data or to perform an action. It includes an endpoint, method, headers, and sometimes a payload; the server returns a status and response data.

REST vs RPC: which model should I use?

REST is resource-oriented and easy to cache and inspect; RPC is procedural and can be simpler for calling node functions (for example, blockchain RPC endpoints). Choose based on the data shape, latency needs, and provider options.

How do I handle rate limits and 429 errors?

Implement exponential backoff, respect Retry-After headers when provided, batch requests where possible, and use caching to reduce repeated queries. Monitoring helps you adapt request rates before limits are hit.

How should I secure API keys?

Store keys in server-side environments or secrets managers, rotate keys regularly, limit scopes, and never commit them to source control. Use environment variables and access controls to minimize exposure.

What tools help test and debug api calls?

Postman, curl, HTTP client libraries, OpenAPI validators, and request-tracing tools are useful. Unit and integration tests with mocked responses catch regressions early.

Disclaimer

This article is for educational and informational purposes only. It explains technical concepts related to api calls and integration practices and does not provide financial, investment, or trading advice. Readers should conduct their own research and consult appropriate professionals before acting on technical or market-related information.

Research

APIs Explained: How Interfaces Power Modern Apps

Token Metrics Team
5
MIN

Every modern app, website, or AI agent depends on a set of invisible connectors that move data and commands between systems. These connectors—APIs—define how software talks to software. This post breaks down what an API is, how different API styles work, why they matter in crypto and AI, and practical steps to evaluate and use APIs responsibly.

What is an API?

An API (application programming interface) is a formalized set of rules and specifications that lets one software component interact with another. Rather than exposing internal code or databases, an API provides a defined surface: endpoints, request formats, response schemas, and error codes. Think of it as a contract between systems: you ask for data or an action in a specified way, and the provider responds in a predictable format.

APIs reduce friction when integrating services. They standardize access to functionality (like payment processing, identity verification, or market data) so developers can build on top of existing systems instead of reinventing core features. Because APIs abstract complexity, they enable modular design, encourage reusability, and accelerate development cycles.

How APIs work — technical overview

At a technical level, APIs expose endpoints over transport protocols (commonly HTTPS). Clients send requests—often with authentication tokens, query parameters, and request bodies—and servers return structured responses (JSON or XML). Key architectural patterns include:

  • REST: Resource-oriented, uses standard HTTP verbs (GET, POST, PUT, DELETE), and typically returns JSON. It's simple and cache-friendly.
  • GraphQL: A query language that lets clients request exactly the fields they need, minimizing over-fetching.
  • WebSocket / Streaming APIs: Persistent connections for real-time data push, useful for live feeds and low-latency updates.
  • RPC / gRPC: Procedure-call style with strong typing and high performance, common in internal microservices.

Operationally, important supporting features include rate limits, API keys or OAuth for authentication, versioning strategies, and standardized error handling. Observability—metrics, logging, and tracing—is critical to diagnose integration issues and ensure reliability.

APIs in crypto and AI — practical examples

In crypto ecosystems, APIs provide price feeds, historical market data, on-chain metrics, wallet services, and order execution. For AI-driven agents, APIs enable access to compute, models, and third-party signals. Example uses:

  • Fetching real-time and historical price data to power dashboards and analytics.
  • Querying on-chain explorers for transaction and address activity for compliance or research.
  • Integrating identity or KYC providers to verify users without handling sensitive documents directly.
  • Calling AI model APIs to generate embeddings, summaries, or predictions used by downstream workflows.

Tools that combine market data, on-chain insights, and AI-driven analysis can streamline research workflows. For example, AI research platforms and data APIs help synthesize signals and surface trends faster. When referencing such platforms in research or product development, it is best practice to evaluate their documentation, data sources, and rate limits carefully. One example of an AI research offering is Token Metrics, which illustrates how analytics and model-driven insights can be presented via a service interface.

Choosing & using APIs: a research checklist

When evaluating an API for a project, consider these practical criteria:

  1. Documentation quality: Clear examples, SDKs, response schemas, and error cases reduce integration time.
  2. Data provenance: Understand sources, update frequency, and any aggregation or normalization applied.
  3. Authentication & permissions: Which auth methods are supported? Can access be scoped and rotated?
  4. Rate limits & pricing: Are limits suitable for your expected throughput, and is pricing predictable?
  5. Latency & uptime SLAs: Critical for real-time systems; check historical status and monitoring APIs.
  6. Security practices: Encryption in transit, secure storage of keys, and breach disclosure policies.
  7. Versioning & backward compatibility: How does the provider manage breaking changes?

Implementation tips: sandbox first, validate edge cases (timeouts, partial responses), and build exponential backoff for retries. For production systems, segregate API keys by environment and rotate credentials regularly.

Build Smarter Crypto Apps & AI Agents with Token Metrics

Token Metrics provides real-time prices, trading signals, and on-chain insights all from one powerful API. Grab a Free API Key

FAQ: What is an API?

Q: What is the difference between an API and a web service?
A: A web service is a type of API accessed over a network using web protocols. APIs can be broader, including libraries and OS-level interfaces; web services are specifically networked services.

FAQ: How do APIs secure communication?

Q: How are APIs secured?
A: Common methods include HTTPS for encryption, API keys or OAuth for authentication, scopes to limit access, and rate limiting to reduce abuse. Proper key management and least-privilege access are essential.

FAQ: REST vs GraphQL — when to use which?

Q: When is REST preferable to GraphQL?
A: REST is simple and widely supported—good for standardized CRUD operations and caching. GraphQL excels when clients need flexible queries and want to minimize over-fetching, but it adds complexity on the server side.

FAQ: Can APIs be used for crypto trading?

Q: Are APIs used to place trades?
A: Many exchange APIs allow programmatic order placement, market data retrieval, and account management. Using them requires careful handling of authentication, error states, and adherence to exchange rate limits and terms of service.

FAQ: How to evaluate an API for a project?

Q: What steps help evaluate an API?
A: Review docs, test a sandbox, verify data lineage and SLA, estimate costs at scale, and ensure the provider follows security and versioning best practices before integrating.

Disclaimer

This article is educational and informational only. It does not constitute investment advice, trading recommendations, or endorsements of any specific products or services. Always perform your own due diligence and comply with applicable laws and platform terms when using APIs or building systems that interact with financial markets.

Research

APIs Explained: How They Work and Why They Matter

Token Metrics Team
5
MIN

APIs power modern software: they let apps talk to each other, enable data sharing, and underpin many AI and crypto services. Whether you use a weather widget, connect to a payment gateway, or build an AI agent that queries market data, understanding what an API is will make you a smarter builder and researcher.

What is an API? A concise definition

An API, or application programming interface, is a set of rules and contracts that lets one software component request services or data from another. Think of an API as a menu at a restaurant: it lists operations you can ask for (endpoints), the inputs required (parameters), and the outputs you’ll receive (responses). The menu hides the kitchen’s complexity while enabling reliable interactions.

At a technical level, APIs define:

  • Endpoints: addressable paths (e.g., /v1/price) that expose functionality.
  • Methods: actions (GET, POST, PUT, DELETE) that describe intent.
  • Payloads and formats: how data is sent and returned (JSON, XML, protobuf).
  • Authentication and rate limits: controls that protect providers and consumers.

How APIs work: protocols, formats, and patterns

APIs come in many flavors, but several common patterns and technologies recur. HTTP-based REST APIs are ubiquitous: clients send HTTP requests to endpoints, and servers return structured responses. GraphQL provides a flexible query language so clients request exactly the data they need. gRPC and protobuf offer high-performance binary protocols suited for internal systems.

Key technical considerations include:

  • Authentication: API keys, OAuth 2.0, and signed requests verify identity.
  • Data formats: JSON is common for public APIs; compact formats (protobuf) are used for efficiency.
  • Versioning: /v1/, /v2/ patterns prevent breaking changes for consumers.
  • Error handling: HTTP status codes and descriptive error bodies aid debugging.

From a user perspective, well-designed APIs are predictable, documented, and testable. Tools like Postman, curl, and OpenAPI (Swagger) specs help developers explore capabilities and simulate workflows before writing production code.

Types of APIs and common use cases

APIs fall into categories by audience and purpose: public (open) APIs available to external developers, partner APIs for trusted integrations, and private/internal APIs for microservices inside an organization. Use cases span virtually every industry:

  • Web and mobile apps: fetch user data, manage authentication, or render dynamic content.
  • Payments and identity: integrate payment processors or single-sign-on providers.
  • AI and data services: call model inference endpoints, fetch embeddings, or retrieve labeled datasets.
  • Crypto and Web3: query blockchain state, streaming market data, or execute on-chain reads via node and indexer APIs.

For crypto developers, specialized endpoints like on-chain transaction lookups, token metadata, and real-time price feeds are common. Choosing the right API type and provider depends on latency, data freshness, cost, and reliability requirements.

How to evaluate and use an API effectively

Selecting an API is a mix of technical and operational checks. Use a framework to compare candidates across functionality, quality, and governance:

  1. Functional fit: Does the API expose the endpoints and data shapes you need? Can it filter, paginate, or aggregate appropriately?
  2. Performance: Measure latency, throughput, and SLA guarantees. For real-time systems, prefer providers with streaming or websocket options.
  3. Data quality & provenance: Verify how data is sourced and updated. For analytical work, consistent timestamps and clear versioning are critical.
  4. Security & compliance: Check authentication methods, encryption in transit, and data-handling policies.
  5. Cost & rate limits: Understand pricing tiers, request quotas, and backoff strategies.
  6. Documentation & community: Good docs, SDKs, and examples reduce integration time and maintenance risk.

When building prototypes, use sandbox or free tiers to validate assumptions. Instrument usage with logging and observability so you can detect schema changes or degraded data quality quickly. For AI agents, prefer APIs that return structured, consistent responses to reduce post-processing needs.

Build Smarter Crypto Apps & AI Agents with Token Metrics

Token Metrics provides real-time prices, trading signals, and on-chain insights all from one powerful API. Grab a Free API Key

FAQ — What is an API?

An API is a contract that allows software components to interact. It specifies endpoints, request formats, authentication, and expected responses so different systems can communicate reliably.

How do I start using an API?

Begin by reading the provider’s documentation, obtain any required credentials (API key or OAuth token), and make simple test calls with curl or Postman. Use SDKs if available to accelerate development.

What’s the difference between REST and GraphQL?

REST exposes fixed endpoints returning predefined data structures, while GraphQL lets clients query for exactly the fields they need. REST is simple and cache-friendly; GraphQL provides flexibility at the cost of more complex server logic.

Are APIs secure to use for sensitive data?

APIs can be secure if they use strong authentication (OAuth, signed requests), TLS encryption, access controls, and proper rate limiting. Review the provider’s security practices and compliance certifications for sensitive use cases.

How are APIs used with AI and agents?

AI systems call APIs to fetch data, request model inferences, or enrich contexts. Stable, well-documented APIs with predictable schemas reduce the need for complex parsing and improve reliability of AI agents.

Disclaimer

This article is for educational purposes only. It explains technical concepts and evaluation frameworks but is not investment advice or a recommendation to use any specific API for financial decisions. Always review terms of service and data governance policies before integrating third-party APIs.

Choose from Platinum, Gold, and Silver packages
Reach with 25–30% open rates and 0.5–1% CTR
Craft your own custom ad—from banners to tailored copy
Perfect for Crypto Exchanges, SaaS Tools, DeFi, and AI Products