Crypto Basics

Are There Crypto Indices for DeFi, AI, and Other Sectors? Exploring Thematic Index Investing in 2025

Want exposure to trending crypto themes like DeFi, AI, and Memecoins? Learn about the top sector-based crypto indices in 2025 and how to invest in the best narratives with less risk.
Token Metrics Team
8 min
MIN

In the fast-moving world of crypto, one of the smartest ways to invest in 2025 is by aligning your portfolio with emerging narratives. Whether it’s DeFi, AI, Memecoins, or Real World Assets (RWAs), crypto’s growth is fueled by themes—and the easiest way to capitalize on them is through sector-based crypto indices.

But are there crypto indices tailored to specific sectors?
Absolutely. In fact, thematic crypto indices are one of the hottest trends in index-based investing right now.

This article explores the most popular sector-based crypto indices in 2025, how they work, and how you can use them to build a diversified, trend-aligned portfolio.

What Is a Thematic or Sector-Based Crypto Index?

A sector-based crypto index is a basket of cryptocurrencies selected based on a specific theme or market narrative. Instead of tracking the overall market, these indices focus on high-growth areas such as:

  • Decentralized Finance (DeFi)
  • Artificial Intelligence (AI) Tokens
  • Memecoins
  • Real World Assets (RWA)
  • Layer 1 Blockchains
  • Gaming / Metaverse

Each index includes multiple tokens within that category, allowing investors to gain exposure to the entire theme without picking individual winners.

Why Sector Indices Matter in 2025

In today’s market, performance is narrative-driven. A single meme can send a coin flying, or a regulatory shift can pump RWAs. Sector indices help investors:

âś… Capitalize on trends early
âś… Avoid single-token risk
âś… Ride sector momentum without constant research
âś… Balance exposure across tokens within a theme

Instead of trying to guess which AI token will win, you can hold the AI Index and benefit from the entire trend.

Top Sector-Based Crypto Indices in 2025

Here are the most popular and best-performing thematic indices this year:

1. Token Metrics AI Tokens Index

Focus: Artificial Intelligence & Agent Economy
Constituents: FET, AGIX, GRT, TAO, NUM, OCEAN
Management: AI-powered with weekly rebalancing

Why It’s Hot:
AI is dominating tech and crypto alike. This index tracks high-conviction AI tokens and rotates into bullish ones each week. Its performance outpaced most passive indices during Q1 2025.

2. Token Metrics DeFi Index

Focus: Core DeFi protocols
Constituents: AAVE, LDO, UNI, RUNE, DYDX, GMX
Management: AI-managed, rebalanced weekly

Why It’s Hot:
DeFi is crypto’s infrastructure. This index rotates into projects showing strength in TVL, volume, and sentiment—giving you DeFi exposure without the need to manage protocol risk manually.

3. Token Metrics Memecoin Index

Focus: Viral meme tokens
Constituents: DOGE, SHIB, PEPE, WIF, BONK, FLOKI
Management: AI-powered signals and weekly adjustments

Why It’s Hot:
This index tracks social momentum and market sentiment, allowing traders to ride the waves while mitigating downside through AI-powered exits.

4. Token Metrics RWA Index

Focus: Real World Asset tokens
Constituents: MKR, ONDO, POLYX, XDC, CFG
Management: Thematic + risk-adjusted AI overlay

Why It’s Hot:
The RWA narrative is exploding as institutions tokenize bonds, treasuries, and assets. This index includes top-performing RWA projects with liquidity and regulatory traction.

5. Token Metrics Layer 1 Index

Focus: Smart contract platforms
Constituents: ETH, SOL, AVAX, NEAR, SUI, TON
Management: Passive or AI-optimized version

Why It’s Hot:
The infrastructure battle among Layer 1s continues. This index provides broad exposure to the platforms that power most of Web3.

6. Index Coop DPI (DeFi Pulse Index)

Focus: Leading Ethereum DeFi protocols
Constituents: AAVE, UNI, COMP, SNX, LRC
Management: DAO-governed, passive rebalance

Why It’s Hot:
DPI is the OG DeFi index—trusted, decentralized, and consistently rebalanced on-chain.

7. Phuture Custom Indices

Focus: User-created strategies
Constituents: Fully customizable
Management: On-chain rules, community-driven

Why It’s Hot:
Create your own sector index or invest in curated strategies. Fully composable within DeFi.

How to Choose the Right Sector Index

Choosing the best sector-based index depends on your goals and your belief in specific narratives.

AI vs. Passive Sector Indices

Many sector indices today are AI-powered, meaning they adjust weights and tokens dynamically based on real-time data. This is especially useful in volatile or hype-driven narratives (like Memecoins or AI tokens).

Where to Invest in Sector-Based Indices

Here’s where to find and invest in thematic indices:

  • âś… Token Metrics – Sector-specific AI indices with weekly signals
  • âś… Index Coop – Ethereum-based DeFi indices with DAO governance
  • âś… Phuture – On-chain, user-customized index strategies
  • âś… Set Protocol – Technical and trend-driven portfolios
  • âś… Centralized Brokers – Limited thematic access (e.g., Bitwise)

You can access these using fiat, stablecoins, or crypto wallets depending on the platform.

Final Thoughts: Sector Indices Help You Invest in What Matters

In 2025, the biggest opportunities in crypto are often found in narrative-driven sectors. Whether it’s AI, DeFi, Memecoins, or tokenized real-world assets, sector-based crypto indices offer:

  • Smart diversification
  • Aligned exposure to growing trends
  • Hands-free portfolio management
  • Reduced risk of picking the wrong token

For the best results, explore platforms like Token Metrics, where AI-enhanced sector indices help you adapt to the market and capitalize on breakout themes with data-backed precision.

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Token Metrics Team
Token Metrics Team

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Here are some of our top picks, based on fundamentals, traction, and longevity.

1. Grass – AI + Revenue

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2. Peaq – DePIN Infrastructure

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3. Sui – Consumer-Focused L1

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4. Parcl – Real Estate Derivatives

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5. BitTensor – AI Infrastructure Layer

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Bonus Mentions:

  • Uniswap / Aave / Compound – battle-tested DeFi with upcoming fee-sharing upgrades

  • Chainlink – oracle king still dominating infrastructure

  • Hyperliquid – sustainable revenue, EVM chain, and perps dominance

Final Words

The 2025 bull market will create noise—but also opportunity. These tokens aren’t just trendy—they’re infrastructure plays with real utility and upside. Allocate accordingly.

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SUI, a rising Layer 1 blockchain network, has been gaining traction recently—and Token Metrics' AI-powered tools were ahead of the curve in identifying its bullish momentum. On April 24th, the Token Metrics Trader Grade issued a bullish signal for SUI, and since then, the price has climbed nearly 22%, confirming the strength of the short-term trend.

But there’s more to this move than just price action. Token Metrics offers a unique perspective by analyzing both short-term and long-term signals through its proprietary Trader Grade and Investor Grade ratings. These grades offer a layered view of an asset's potential by using machine learning to evaluate over 80 on-chain, off-chain, and technical indicators.

Token Metrics AI: Bullish for Traders, Bearish for Investors

As of the latest data, SUI holds a “Strong Buy” rating on the Token Metrics Trader Grade, signaling powerful momentum for short-term traders. This suggests that swing traders and scalpers could benefit from the current trend, particularly if the price can decisively break through the immediate resistance at $4.25.

However, the Investor Grade tells a different story. While the short-term outlook is bullish, the long-term view remains cautious. The Investor Grade currently recommends a Sell, suggesting SUI may face challenges in sustaining gains over a multi-month time frame. This divergence highlights the importance of aligning your investment strategy with the appropriate time horizon.

TVL Growth Validates SUI’s Ecosystem Expansion

Beyond AI ratings, Token Metrics also factors in fundamental metrics—and one of the strongest tailwinds for SUI right now is its rapidly growing Total Value Locked (TVL). According to DeFi Llama, SUI’s TVL has surged to a new all-time high of $2.11 billion, cementing its position as the 8th largest blockchain by TVL.

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Key Technical Levels: Breakout or Pullback?

From a technical analysis standpoint, SUI is now testing a major resistance at $4.25. A confirmed breakout above this level could send the asset surging toward new all-time highs, potentially igniting a new wave of momentum-driven buying.

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The crypto market is cyclical—not just in price, but in narrative. In recent months, attention has rotated from AI to DeFi, creating new opportunities for savvy investors. Let’s break down the trends.

AI Momentum Remains Strong

Projects like Vader AI, BitTensor, and Grass continue to dominate the conversation. Vader AI, part of the Virtua ecosystem, gained momentum from staking programs and Genesis Launchpad allocations. Grass, a data-layer AI protocol, claims $15M+ in revenue and recently flipped bullish on technical indicators.

BitTensor remains the leading infrastructure play in the AI space, drawing parallels to Bitcoin in its community enthusiasm and decentralization ethos. It has rebounded over 150% from its lows and is showing resilience in the current market cycle.

DeFi’s Comeback: Aerodrome and Beyond

Meanwhile, DeFi is showing signs of resurgence. Aerodrome, a DEX on the Base chain, is gaining traction through strong liquidity incentives and revenue-sharing mechanisms. Its user incentives echo the early days of Curve or Uniswap but on a chain optimized for scalability.

Virtua’s staking model is also driving a hybrid DeFi/AI strategy, blurring the lines between token utility, participation, and value capture.

Narrative Rotation: What It Means

Crypto narratives are rarely zero-sum. What we’re seeing now is a healthy diversification: AI remains dominant, but DeFi is catching a second wind. For investors, this means exploring tokens that sit at the intersection—offering strong tech, compelling incentives, and infrastructure integrations.

Closing Thoughts

Whether you’re riding the AI wave or positioning for the DeFi rebound, it’s clear that smart capital is flowing into ecosystems with tangible traction. Watch the flows, track the signals, and always be ready to pivot.

Track the Trends with Token Metrics

Token Metrics is your edge in navigating the ever-shifting landscape of crypto narratives. Our AI-powered research platform helps you spot bullish trends early, evaluate project fundamentals, and make data-driven investment decisions. Whether you're interested in AI tokens, DeFi protocols, or hybrid plays, Token Metrics provides real-time signals, technical grades, and curated indices to guide your next move.

Explore the platform at www.tokenmetrics.com and discover where smart capital is heading next.

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